Fully up to date publication list on Google Scholar
Research articles (* denotes co-first authors)
Bonazza, S., Turkington, H.L., Coutts, H.L., Sukumar, S., Hawthorn, C., Getty, E.M.P.E., Touzelet, O., Barabas, J., Power, U.F., Courtney, D.G. 2024 Myoferlin is an essential component of late-stage vRNP trafficking vesicles for enveloped RNA viruses. Under revision and available on bioRxiv at https://doi.org/10.1101/2024.07.02.601679
Coutts, H.L., Turkington, H.L., Bonazza, S., Getty, E.M.P., Sukumar, S., Power, U.F., Courtney, D.G. 2024 The cold-inducible RNA-binding protein RBM3 stabilises viral mRNA at the cooler temperatures of the upper respiratory tract. Under submission and available on bioRxiv at https://doi.org/10.1101/2024.07.25.605104
Bonazza, S., Coutts, H., Sukumar, S., Turkington, H., Courtney, D. G. 2024 Identifying cellular RNA-binding proteins during infection uncovers a role for MKRN2 in influenza mRNA trafficking. PLoS Pathogens. https://doi.org/10.1371/journal.ppat.1012231
Coutts, L.H., and Courtney, D.G. 2024 Identifying individual Pseudouridine (Ψ) sites across transcripts from HIV-1 infected cells. In: Prasad, V.R., Kalpana, G.V. (eds) HIV Protocols. Methods in Molecular Biology, vol 2807. https://doi.org/10.1007/978-1-0716-3862-0_16
Dupont, M., Krischuns, T., Giai-Gianetto, Q., Paisant, S., Bonazza, S., Brault, J., Douché, T., Perez-Perri, J, I., Hentze, M. W., Cusack, S., Matondo, M., Isel, C., Courtney, D. G., Naffakh, N. 2023 The RBPome of influenza A virus NP-mRNA reveals a role for TDP-43 in viral replication. Nucleic Acid Research. gkae291, https://doi.org/10.1093/nar/gkae291
Chen, K., Krischuns, T., Varga, L. O., Harigua-Souiai, E., Paisant, S., Zettor, A., Chiaravalli, J., Delpal, A., Courtney, D. G., et al. 2022 A highly sensitive cell-based luciferase assay for high-throughput automated screening of SARS-CoV-2 nsp5/3CLpro inhibitors. Antiviral Research. 201, 105272.
Broadbent, L., Connor GG Bamford, C. G. G., Lopez Campos, G., Manzoor, S., Courtney, D.G., Ali, A., Touzelet, O., McCaughey, C., Mills, K., Power, U. F. 2022 An endogenously activated antiviral state restricts SARS-CoV-2 infection in differentiated primary airway epithelial cells. PLoS ONE. 17(4): e0266412.
Bamford, C. G. G., Broadbent, L., Aranday-Cortes, E., McCabe, M., McKenna, J., Courtney, D. G., et al. 2022 Comparison of SARS-CoV-2 Evolution in Paediatric Primary Airway Epithelial Cell Cultures Compared with Vero-Derived Cell Lines. Viruses. 14 (2), 325.
Martinez Campos, C., Tsai, K., Courtney, D. G., et al., 2021 Mapping of pseudouridine residues on cellular and viral transcripts using a novel antibody-based technique. RNA. 27 (11), 1400-11.
Courtney, D.G., Tsai, K., Bogerd, H.P., et al. 2019 Epitranscriptomic regulation of HIV-1 gene expression by m5C . Cell Host & Microbe 26 (2), 217-227.
Courtney, D.G., Chalem, A., Bogerd, H.P., et al. 2019 Extensive epitranscriptomic methylation of A and C residues on murine leukemia virus transcripts enhances viral gene expression. mBio 10 (3), e01209-19.
Maurizi, E., Schiroli, D., Atkinson, S.D., Mairs, L., Courtney, D.G., O'Hagan, B., et al. 2019 A novel role for CRIM1 in the corneal response to UV and pterygium development. Experimental Eye Research 179, 75-92.
Tsai, K., Courtney, D.G., Kennedy, E.M., Cullen, B.R. 2018 Influenza A virus-derived siRNAs increase in the absence of NS1 yet fail to inhibit virus replication. RNA 066332.118
Tsai, K., Courtney, D.G., Cullen, B.R. 2017 Addition of m6A to SV40 late mRNAs enhances viral structural gene expression and replication. Plos Pathogens 14(2): e1006919.
Christie, K.A., Courtney, D.G., DeDionisio, L.A., et al. 2017 Towards personalised allele-specific CRISPR gene editing to treat autosomal dominant disorders. Scientific Reports. 7 (1), 16174.
Courtney, D.G., Kennedy, E.M., Dumm, R.E., et al. 2017 Epitranscriptomic enhancement of influenza A virus gene expression and replication. Cell Host & Microbe. 22 (3), 377-386.
*Allen, E.H.A., *Courtney, D.G., Atkinson, S.D., et al. 2016 Keratin 12 missense mutation induces the unfolded protein response and apoptosis in Meesmann epithelial corneal dystrophy. Human Molecular Genetics. 25 (6), 1176-1191.
Courtney, D.G., Moore, J.E., Atkinson, S.D., et al. 2015 CRISPR/Cas9 DNA cleavage at SNP-derived PAM enables both in vitro and in vivo KRT12 mutation-specific targeting. Gene Therapy. 23 (1), 108-112.
Courtney, D.G., Toftgaard Poulsen, E., Kennedy, S., et al. 2015 Protein Composition of TGFBI-R124C- and TGFBI-R555W- Associated Aggregates Suggests Multiple Mechanisms Leading to Lattice and Granular Corneal Dystrophy. Invest. Ophthalmol. Vis. Sci. 56, 4653–4661.
Courtney, D.G., Atkinson, S.D., Allen, E.H.A., et al. 2014 siRNA Silencing of the Mutant Keratin 12 Allele in Corneal Limbal Epithelial Cells Grown from Patients with Meesmann’s Epithelial Corneal Dystrophy. Invest. Ophthalmol. Vis. Sci. 55, 3352–60.
Courtney, D.G., Atkinson, S.D., Moore, J.E., et al. 2014 Development of allele specific gene silencing siRNAs for TGFBI Arg124Cys in Lattice Corneal Dystrophy Type I. Invest. Ophthalmol. Vis. Sci. 55, 977-985.
Moore, J.E., Atkinson, S.D., Azar, D.T., Worthington, J., Downes, C.S., Courtney, D.G., Moore, C.B.T. 2014 Protection of corneal epithelial stem cells prevents ultraviolet A damage during corneal collagen cross-linking treatment for keratoconus. Br. J. Ophthalmol. 98, 270–4.
Review articles
Courtney, D. G., 2021 Post-transcriptional regulation of viral RNA through epitranscriptional modification. Cells. 10 (5) 1129.
Kennedy, E.M., Courtney, D.G., Tsai, K., Cullen, B.R. 2017 Viral Epitranscriptomics. Journal of Virology. 91 (9), e02263-16.
Courtney, D.G., Thakur, A., Nesbit, M.A., et al. 2015 A review of personalised molecular medicine for the treatment of corneal disorders. Int J Ophthalmol Eye Res. S2:001, 7-18.